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In help for a job of an important use of glycogen for Na,K-ATPase, it has been demonstrated that, in astrocytes, glycogen is a critical vitality source for neurons with significant implications in mind function, i.e. synaptic exercise and memory formation (Obel et al. SR? A consequence of microenvironments with excessive ATPase activity and the restricted diffusability within the muscle cell is the need to compartmentalize metabolic pathways. In other words, the primary ATPases rely on a structural organization of substrate and metabolic enzymes in the direct neighborhood and cannot rely on simple diffusion (Ovadi & Saks, 2004). Thus, distinct channelling of the intermediates from the substrate by means of enzymatic pathways and transfer of ATP to the metabolically energetic websites will ensure a enough metabolic energy without the necessity of free diffusion. Consistent with this, glycogen particles are present in distinct places within this organization together with just beneath the plasma membrane, near SR and mitochondria, and within the myofibrils between the contractile filaments.

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